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Ranitidine (Ranitidine) instructions for use, price, description, composition
The active substance (INN) Ranitidine (Ranitidine)
Application: Stomach ulcer and duodenal ulcer (treatment and prevention), NSAID-gastropathy, post-operative ulcer, reflux esophagitis, Zollinger - Ellison syndrome, chronic dyspepsia with epigastric and retrosternal pain, prevention of stress ulcers, recurrent bleeding, Mendelson syndrome.
Contraindications: Hypersensitivity, liver cirrhosis with portosystemic encephalopathy, a history of abnormal liver function and kidney failure, pregnancy, breast-feeding (the period of treatment stop), children's age (14 years).
Side effects: Headache, dizziness, vertigo, drowsiness, anxiety, agitation, depression, hallucinations (mainly in severely ill and the elderly), reversible blurred vision, involuntary movements, arrhythmias (tachycardia, bradycardia, asystole, AV block, extrasystoles) constipation or diarrhea, nausea, vomiting, abdominal pain, pancreatitis, hepatocellular, cholestatic or mixed hepatitis with jaundice or without arthralgia and myalgia, increase of creatinine in the blood, leukopenia, granulocytopenia, thrombocytopenia, agranulocytosis, pancytopenia, bone marrow hypoplasia and aplastic anemia, immune hemolytic anemia, gynecomastia, impotence, decreased libido, alopecia, rash, erythema multiforme, angioedema, anaphylaxis.
Interactions: Antacids and sucralfate may reduce absorption. Alter the absorption and excretion of other drugs (in accordance with their acid-base properties).
Overdose: Treatment: induction of vomiting or gastric lavage, in convulsions - diazepam IV, at a bradycardia - atropine, and ventricular arrhythmias - lidocaine.
Dosage and administration: Orally, daily at 150 mg 2 times daily or 300 mg at bedtime. When erosive esophagitis - 150 mg 4 times a day, the maximum allowable dose for adults - 6 g / day.
Children to designate the interior of 2-4 mg / kg 2 times a day with a stomach ulcer and duodenal ulcer (maximum - 300 mg / day), and reflux esophagitis - 2.8 mg / kg 3 times a day. V / m, iv, 50 mg every 6-8 hours
Precautions: use with caution in patients with impaired renal function, with porphyria (in history) and in children. Before starting treatment should be to exclude the presence of malignant neoplasms in the stomach and duodenum. In elderly patients with impaired liver or kidney function may disorder (confusion) of consciousness, necessitating dose reduction. Instant tablets contain sodium, which should be considered when assigning patients who have shown the restriction of its reception, and aspartame undesirable for patients with phenylketonuria.
